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- Unlocking the secrets of cellular uptake: paving the way for new cancer and disease treatmentsDrug development is a balancing act between ensuring that the drug is suitable for the target and that the drug can penetrate the cell membrane to reach the target. Typically, research into drugs that can cross cell membranes has focused on small, rigid molecules with nonpolar chemical structures. However, new therapeutic strategies break traditional drug design rules by using larger, flexibly...0 Comments 0 SharesPlease log in to like, share and comment!
- Mechanisms by which FOXA2 Drives Prostate Tumor Cell Plasticity and Activation of the KIT Signaling PathwayOn November 3, Cancer Cell published online a research paper entitled "FOXA2 lineage plasticity drives and KIT pathway activation in neuroendocrine prostate cancer" by Gao Dong's research group at the Center for Excellent Innovation in Molecular Cell Science, Chinese Academy of Sciences. This study reveals the key role of FOXA2 in regulating the transition of prostate adenocarcinoma to...0 Comments 0 Shares
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