Spatial Genomics & Transcriptomics Industry Overview

The global spatial genomics and transcriptomics market size was valued at USD 163.8 million in 2020 and is expected to expand at a CAGR of 11.1% from 2021 to 2028. 

Architecture analysis of genome content in histological specimens is considered a cornerstone in several biomedical research and diagnostics. This is effectively addressed by the advent of spatial omics as a technology-driven field that involves the determination of high-throughput omics data procured from tissue and cell specimens, along with data for the organizational structure of cell content, resulting in the revenue growth of the market. Technologies being introduced in this market are a result of convergence between conventional imaging technologies and novel high-throughput sequencing technologies with methods that help determine positional information of DNAs and RNAs. Although this field holds significant potential in disease management, spatially resolved omics need better implementation for the development of new methods to boost the market growth. 

Gather more insights about the market drivers, restrains and growth of the Global Spatial Genomics & Transcriptomics Market

Moreover, key market players are focused on expanding their spatial transcriptomics and genomics footprints by entering into strategic partnerships and collaborations with other players. Moreover, the companies are undertaking strategies to expand their customer base across the globe. For instance, in February 2020, Dovetail Genomics announced the global availability of its Dovetail HiChIP and Micro-C Kits.

Dovetail Micro-C kits provide a better resolution of chromatin contacts at a mononucleosome level, whereas HiChIP technology combines the Micro-C and ChIP-seq into one workflow, which allows assaying protein-directed alterations to chromatin architecture, enabling assessment of its impact on gene expression.

The onset of COVID-19 has partially offset the revenue growth of operating market players. However, NanoString’s GeoMx Digital Spatial Profiling accelerates SARS-CoV-2 research as it is well established to operate using FFPE samples—specimens that are being provided by COVID-19 autopsies. Thus, the current global pandemic has created considerable opportunities for the market players operating in the space.

Browse through Grand View Research's Biotechnology Industry Research Reports.

  • Gene Expression Market - The global gene expression market size was valued at USD 9.07 billion in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 9.96% from 2021 to 2028. The development of technologically advanced solutions is anticipated to provide growth avenues to this market. For instance, in May 2020, 10x Genomics, Inc. launched 10x-targeted single-cell RNA sequencing, the company’s targeted gene expression solution for spatial genomics and single-cell analysis.
  • Genomics Market - The global genomics market size was valued at USD 20.1 billion in 2020 and is expected to expand at a compound annual growth rate (CAGR) of 15.35% from 2021 to 2028. The scientific community has tried to address genetic susceptibility and severity to SARS-CoV-2 infection by combining research efforts using existing genetic databases. Multiomic-based approaches and genome-wide association studies (GWAS) have been employed to uncover biological networks and common variants underlying host-pathogen interactions.

Spatial Genomics & Transcriptomics Market Segmentation

Grand View Research has segmented the global spatial genomics and transcriptomics market on the basis of technology, product, end-use, and region:

  • Spatial Genomics & Transcriptomics Technology Outlook (Revenue, USD Thousand, 2017 - 2028)
    1. Spatial Transcriptomics
      1. Sequencing-based Methods
        1. Laser Capture Microdissection (LCM)
          1. FFPE Tissue Samples
          2. Others
        2. Transcriptome In-vivo Analysis (TIVA)
        3. In Situ Sequencing
        4. Microtomy Sequencing
      2. IHC
      3. Microscopy-based RNA Imaging Techniques
        1. Single Molecule RNA Fluorescence In-situ Hybridization (smFISH)
        2. Padlock Probes/ Rolling Circle Amplification
        3. Branched DNA Probes
    2. Spatial Genomics
      1. FISH
      2. Microscopy-based Live DNA Imaging
      3. Genome Perturbation Tools
      4. Massively-parallel Sequencing
      5. Biochemical Techniques
      6. Others
  • Spatial Genomics & Transcriptomics Product Outlook (Revenue, USD Thousand, 2017 - 2028)
    1. Instruments
      1. By Mode
        1. Automated
        2. Semi-automated
        3. Manual
      2. By Type
        1. Sequencing Platforms
        2. IHC
        3. Microscopy
        4. Flow Cytometry
        5. Mass Spectrometry
        6. Others
    2. Consumables
    3. Software
      1. Bioinformatics tools
      2. Imaging tools
      3. Storage and management databases
  • Spatial Genomics & Transcriptomics End-use Outlook (Revenue, USD Thousand, 2017 - 2028)
    1. Translational Research
    2. Academic Customers
    3. Diagnostic Customers
    4. Pharmaceutical Manufacturer
  • Spatial Genomics & Transcriptomics Regional Outlook (Revenue, USD Thousand, 2017 - 2028)
    1. North America
    2. Europe
    3. Asia Pacific
    4. Latin America
    5. Middle East & Africa (MEA)

 Market Share Insights

  • January 2020: Dovetail Genomics expanded its Genome Assembly offerings to include annotations and chromosome-scale assemblies and 3D genome conformation analysis. 
  • February 2020: ReadCoor, Inc. introduced its first product line that includes the RC2 instrument and multi-omic spatial sequencing assays. The instrument deploys the Fluorescent In Situ Sequencing (FISSEQ) technology of the company to operate.

Key Companies profiled:

Some prominent players in the global spatial genomics & transcriptomics market include

  • Natera Inc.
  • 10x Genomics
  • Dovetail Genomics
  • Illumina, Inc.
  • S2 Genomics, Inc.
  • NanoString Technologies, Inc.
  • Seven Bridges Genomics
  • Horizon Discovery Group plc
  • Bio-Techne

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