The global Cystic Fibrosis Drug Market was worth USD 8.85 Billion in 2021 and is predicted to grow at a CAGR of 24.5% during the forecast period. The increase in market revenue is primarily driven by new technological advancements in therapeutic treatments.

Bronchodilator drugs are in high demand for widening airways and relieving symptoms. Cystic fibrosis affects the cells responsible for mucus production and other fluids, which leads to breathing difficulties, thick viscous secretions, and digestive issues.

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The WHO reported that in developed countries, about 50% of children with cystic fibrosis are diagnosed in their first year of life. Research and development of new and advanced drugs, increasing prevalence of cystic fibrosis patients, and rising demand for alternative treatments are the other factors propelling the growth of the cystic fibrosis drugs market.

The major restraint to market growth is the adverse effects of drugs among people. Most CFTR modulators cause side effects like headache, breathing difficulties, nausea, and diarrhea, while pancreatic enzyme supplements produce moderate gastrointestinal problems. Drug interactions and antibiotic use can also produce negative gastrointestinal effects.

The global cystic fibrosis drug market is segmented by drug class into CFTR, bronchodilators, mucolytic, pancreatic enzyme supplements, and others. The CFTR segment is leading in terms of revenue share in 2021. CFTR ion channel in the lung transports chloride ions from within to outside the cell.

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Modulators of cystic fibrosis transmembrane conductance regulator are a class of medications that improve the intracellular processing, production, and function of the faulty CFTR protein, leading to growth in the segment. The triple combination Elexacaftor-Tezacaftor-Ivacaftor is the most commonly used approved modulator.

The global cystic fibrosis drug market is further segmented by route of administration into oral and parenteral. The oral segment is expected to register a significantly fast revenue growth rate over the forecast period. Oral Nutritional Supplements (ONS) are commonly used in people with cystic fibrosis. Docosahexaenoic Acid supplementation for cystic fibrosis patients results in the correction of known fatty acid derangements and decreases the formation of proinflammatory isoprostanes such as 8-isoprostane-PGF2, leading to growth in the segment.

Overall, the increasing demand for bronchodilator drugs and the development of new and advanced drugs are driving market growth, but adverse drug effects are a restraint to market growth. CFTR modulators and oral supplements are leading in terms of revenue share, and the oral route of administration is predicted to register the highest revenue growth rate over the forecast period.

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